Expert opinion: migraine, psychiatric comorbidities, and treatment.

INICAL HISTORY A 28-year-old woman has had migraine without aura since the age of 13 with attacks now occurring about 4 times per month with an inconsistent response to triptans. In addition, she has had recurring endogenous depression for 3 years treated with paroxetine last over one year ago with some help. Her depression is currently mild. There is no history to suggest hypomania or mania. She has been frequently anxious for a few years as well, worrying about everything, which can cause difficulty falling asleep. Her mother has a history of major depression and migraine. Her sister is being treated for migraine and bipolar disease.